I don't think the splines are different. I thought the adapters are the same but I only researched this briefly. You could call marks adapters to confirm. A 4l60e should be good for 200k miles or so Im guessing. Should be a lot of info on 4l60e longevity on the net. I bought my rebuilt one for 900 bucks. The 4l80e is a bit bigger of a housing so its a tighter fit in the trans tunnel of the 80 series. Also the plug on the transmission is different and you have to connect a few more wires to the ecu. I would be hesitant to install a used 4l60e unless money was really tight.