While the transfer case reduction gears are great for slow crawling, hill decents, and steep climbs in offroad, the benefit is limited to low-range only. I look at these as Icing on the cake, as a compliment to proper diff gearing. Not as a substitute. If you are running 33” + on stock gearing you can and WILL benefit from changing the diff gears in High and low range. Running larger tires has the same effect as gearing higher, by reducing RPMs below the ideal operating range. What this does is cause overdrive to become less useful as the vehicle is often down shafting, trying to stay at proper RPM’s, thus running even higher RPMS. This is bad for economy, performance, acceleration, wear & tear etc. So regearing your diffs gets you where you should be in Low & High Range, for offroad and Highway use, the transfercase only benefits for offroad and lowrange. Long story short, if you can afford to, do both. If not, do Diff gears. As for the debate on strength between different ratios, while there is theoretically some compromise, the benefits of the proper gearing far offset them. Additionally a new diff with 4.88 setup properly is going to hold up better than a 4.10 diff with 250k on it.