Nooby here, so take this with a grain of salt (Himalayan Pink Crystal only please) Although I have bled lots of brakes on multiple types of vehicles in the recent past.
The Bleeder valve is almost always at the highest point in the Caliper, so while it is possible some air could flow back into the bleeders around the threads, the bubble would be in a dead end - after the Foot to Piston fluid path.
I too have used the HF Vacuum bleeder, and Mytivac they both get a very small stream of bubbles, from either around the hose itself, or drawn in around the threads.
The Partially filled bottle high up also works, but it makes sense that having a second person pushing on the brake as you close the bleeder would eliminate ANY bubbles