In my travels, Kingsbury grade east of Lake Tahoe takes the cake. 11 miles of single lane switchbacks, the most severe of which is 1900' climb over 6 miles, to an elevation of 7500 ft. Several miles at 5-10% grades, with a section at 10-15% grade. RVs not recommended, and generally take a more northern route to avoid this grade.
Towing 8000lbs with parts slogging 2nd gear full throttle at 35mph.
More power could help, but the other reality is that most every other vehicle is slogging it too. There's very few turnouts on that route and I did take one for the vehicles behind me to pass.
They didn't because they couldn't muster anymore power either.
The 200-series needs no excuses and will do the deed. Have to remember it's a naturally aspirated motor so keeping RPMs in the mid-range is only accessing just over half the potential HP the motor can make.
A turbo motor like an EcoBoost makes better mid-range power, but then again I have no want for an EB with the issues they see. Turbo, supercharged, and diesel motors are working harder with more combustion pressure and heat, needing excess fuel for cooling to stave off detonation, even if it feels like they work less hard with lower RPM.
It's a Toyota, let her spin.