At the risk of sounding like a broken record I am going to chime in again.
So really there are levels or stages that you can look at when you are taking just about any car and adding forced induction. I tried to lay that out a little in the turbo thread from a ways back but maybe I did a poor job.
In the case of the 80 series with OBDII here is how I see them....
Stage 1 - a TRD super charger or a turbo running close to the same amount of air, roughly enough to produce an extra ~70hp/50awhp.
This is the very beginning of forced induction, basically a set and forget setup that relies on the 80's extra rich fueling and stock timing cut.
Stage 2 - Taking the above and adding a smaller pulley or a stiffer wastegate spring to increase boost.
You are now starting to increase IAT's, you are possibly going to start running lean in areas of the fueling map, etc. This is where cooling the air charge with an intercooler and adding something like a water/meth kit to prevent detonation, increase octane, etc should be started.
Stage 3 - You want even more boost, you start leaving the ability of the stock fuel injectors behind.
You can do like lilevo did and scale a larger MAF to a larger fuel injector but that is not ideal. You can replace the fuel injectors and attempt to modify the O2 signal so that the truck thinks it is running lean when it is at stoch and add more fuel via longer injector pulse widths, or you can go with a stand alone to take control of the injectors, wideband and timing.
This is pretty much the extent of tuning an OBDII 80 series, the OBDI trucks are much different as they tend to run lean and even in what I wrote as my stage 1 above, they need quite a large amount of meth injection to make up for the lack of fueling they have when under boost. I knew at one time, but I no longer remember what size Cdan is running for his meth injection on his OBDI truck but it was clearly large enough not to be a charge air cooler but to be a fuel source.