It's always interesting to see the discussion of costs of swaps. Yes, a swap - gas or diesel, can cost $10-20K, but they don't have to.
Read my build, I have less than $2000.00 into my Isuzu swap after selling off my left over parts. I did 90%+ of all the work, it only took 3 weeks of nights and weekends, and then we left with it on 2 week vacation!
I have a factory turbo charged and inter-cooled diesel engine, with PS and AC, that has averaged right at 20 mpg over about 6 years and 50k plus miles. I can cruise at 70+, pass cars on the freeway, go up the 6% grade of the Tejon pass in summer with 3 people, 3 dogs, roof rack, full camping gear for 4 days, with ac in 5th gear at 70 mph! So it ain't bad.
The drive train is not a mesh mash everything but the engine is Toyota. The stock drive line is in the stock locations, the transmission was never removed, DS angles are stock, the radiator is stock, etc. Even the stock 60 top radiator hose is used. Isuzu parts can be bought at any Chevy or GM truck dealer, or at Isuzu. So no issues there.
I have no complaints
PS - With my Saddle Tank, I have a travel range of around 800 miles without refueling!
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