Those Remflex gaskets are outstanding, BTW. Used one on the 225 slant in my '74 Plymouth (notorious for manifold leaks) and never once had an issue afterwards.
As far as the bolt patterns go, though we're hunting different objectives here, it looks like (now someone correct me if I'm wrong) I could use a 3FE gasket, retain the extra bolts on my 3FE head, and possibly drill out the mounting flanges on a set of 2F headers to allow them to mount to a 3FE head (drilling them prior to having them ceramic coated). Connecting to the exhaust is a non issue for me since I'll be having a custom system built that can easily be located to mate to the header outlets.
Why would you want to mount 2F header on a 3FE head when the 3FE exhaust manifold is likely superior to a 2F header?