I assume you mean in the Summer months, right?
DO IT!! You will LOVE it.
My personal rules for Dalton Highway (though it's now been quite a few years past)...
-2nd Spare tire (Can definitely be metal debris hidden on road since it's in a constant state of damage/repair...Saw a guy pop both tires on a side right in front of me.)
-Extra Fuel
-Seriously check vehicle before this trip! You can get help, but it can cost a fortune.
-Don't Forget to Sleep: If you are there in the Summer, it's easy to forget to sleep, because it will still be "evening" up past midnight once you're so far North.
Unsolicited Tips:
Driving:
-Milepost Book is still your friend. Will point out all sorts of cool stuff by the mile...
-Rock Damage Question: I avoided this entirely by simply pulling well to the right if a vehicle passed me...and also by making plenty of room for on-coming big-rigs & avoiding tailing them (most vehicles you see will be huge trucks unless it's gotten more touristy of late...). Running the full length twice, I had no noteworthy rock damage either time.
-If you see standing water next to the road with a bank/drop on the other side...BEWARE! -Total road wash-out could be brewing! (Ask how I know!)
-Lots of wiper fluid & good wipers. When it's wet, your vehicle becomes coated in grey/brown crust.
-Last couple hundred miles to the Arctic Ocean is monotonous. Straight... Tundra... No trees, etc.
-Later in Summer usually means fewer mosquitos... Hard to predict since it's all about standing water and life cycle/thaw dates, etc...
-Brooks Range is incredible. All Sheep let you get very close. I was there in August both times and they weren't bad.
-Wide angle lens, LARGE telephoto lens, tripod. Low-angle sunlight is gorgeous throughout the day if you ever get direct sunlight on your landscape...
(No, your telephoto lens still won't seem long enough for critters... Zoom with your FEET or splurge on that big lens).
-Prudho Bay is no photo-spot (though you gotta take some anyway). Basically an outpost for oil workers. Not set up for tourists, though there is a "motel."
-Firearms: You CAN carry firearms, but getting them through Canada is a problem. You should be able to mail them to a gun shop somewhere...(Don't carry small calibre stuff...it will most likely just tick the bear off. 44Mag with heavy loads or 460/.500 is better. Or shotgun with slugs.
Camping:
-You can basically camp wherever along the way. Respect fragile tundra.
-Bear protection/Smarts (read up from local sources...not "the internets..."

We were in a tent, with multiple Brown/Grizzy not far away... Read up on proper bear behavior & response.
(No, Grizzlies are NOT about to eat you just because they stand on their hind legs.)

Their eyesight is poor & they're just having a look-see. My bro-in-law's friend needlessly killed a bear because he'd seen too many movies of standing bears eating folks...

-No food in tents!
-Be nice to bow hunters (just keep driving if you see them crouched or stalking). They have their work cut out for them trying to close distance on Caribou with so much open tunrdra.
-Daily rain showers common
-We slept IN the vehicle about half the time due to crazy weather.
-If you see rusty animal traps, leave them alone. They will look abandoned and cool, but they are in use--likely by subsistence hunters who really can't afford to replace them. They leave them in their favorite spots, tethered by wires. Taking them reeeeally does those folks damage.
My 1.5 cents. Blah blah blah!
M