Don't be afraid to use 2nd gear on a steep downhill. It won't hurt your engine to rev 5000 RPMs. Use your brakes sparingly to control your speed as needed but if you're riding them you need to slow down a use a lower gear.
Turn your trailer brake controller up. I usually run around ~6 on my redarc but I'll crank up to 8+ on a steep descent. Too high trailer brakes are not ideal for emergency maneuvers but don't hesitate to use them. I don't manually activate mine hardly ever but YMMV.
Yes - I find it rare to get out of S4 even on long trips. S2 and S3 (on 6 speed trans) are normal on long grades, both up and down. Look like you might have a 8 speed so I don't know how that translates. The 5.7 seems like it really hits it's stride at around 4K and has no problem humming away at that speed.
I also have the redarc, and I assume they all tune differently. I run mine around 2-3 and 4 on the steep downhill grades. Above 5 I get lock ups. You will be surprised how small adjustments make a big difference.