Engine's are their most efficient when operated at their peak torque RPM. The term used is "BSFC" or "Brake Specific Fuel Consumption." What that means is that this is the fuel used per HP produced. The lowest BSFC always happens at the Torque peak. So you want to gear the vehicle to put the engine on or a little under it's torque peak rpm when going the cruise speed that you want.
I use OD's. I do not like them. They do not make sense.
Think about what exactly an OD really is. Another set of gears in mesh, turning on additional bearings. There is no way that such a system is more efficient than a straight through coupling. By design an OD has more parasitic loss than does a straight through coupling.
AFAIC transmissions should have a lower first gear combined with a direct high gear. No overdrives. You would end up with the same spread (range) of trans ratios, just all of them moved down to the point that the highest was a direct coupling rather than an OD. Then put a final drive ratio in the vehicle that operates the engine at it's ideal rpm for the intended cruise speed. This also results in lower numeric ratio ring & pinion, which is stronger. If the trans had a lower first gear, then you could run, say, 3.70's instead of 4.56's and still have the crawl ratio that you need while not needing an OD and it's included inefficiencies.