I won't get in to the quintessential 80 vs 100 but here's my thoughts on the 2UZ and some comparisons to the 1FZ.
The 2UZFE is proving itself to be a very solid engine without any real points where you can say "oh this was clearly overengineered" like certain components in an 80 or as another better toyota example, a supra. The engines are in service around the world as we have 100 owners on the board from most of the same countries as the 80 board. The thing is most of our high mileage guys are only in the 1xx,xxx range because the engines are still young, the oldest being a '98. I'm at 14x,xxx and it runs like a top and consumes zero oil and is capable of 12,000+ mile oil change intervals. To me the lack of wear metals and the lack of wear on oil are indicating this to be an extremely well engineered engine. We've really only seen a couple of instances of people that have passed the 2xx,xxx mark but they've all been pleased so far. One was even on his original timing belt!
Timing is a major difference between the 1FZ and the 2UZ and seems to be the cheif talking point. It's seen as a downfall but is more of a difference in maintenance issue. The belt's service interval is 90,000 miles so it's not something you are going to deal with often at all, you're already familiar with the chain so I don't need to touch on that.

I also don't think the belt was so much of a downgrade; most high tolerance multi-valve modern engines run a belt for it's higher precision and smoothness. We have yet to hear of a t-belt failure from any member of the board either.
It appears that the starter is the only real point of contention with the 2UZ that a higher than normal amount of owners are dealing with. It is not seeing the life cycle that it should be. Most are experiencing the contacts wearing between 80k-110k. It's a PITA to change but is a cheap item. A similar situation to headgaskets on an 80. The gasket is el-cheapo but getting to it is not alot of fun. It cost me about $20 in parts from CDan IIRC and took 0.5-1 day to take care of. No more than 0.5 day if you have a helper.
That's pretty much all that comes to my mind although I'm sure there's stuff I've forgotten. I'm only on coffee #1 this morning so I'm not fully functional yet.
Bottom line alot of the overengineered 1FZE items like increased sump capacities, and multiple coolers have been replaced by more efficent engineering designs of the times. The 2UZ has no need for any bigger sump (7.2qt) if it's already 12,000mile OCI capable; it's design is just easier on the oil to start with. I live down a dusty gravel road and have no problems with dust/silicates in the engine oil so I can't see where the air box needs to move to cyclonic action. I've never heard of trannies overheating on a 100 (2UZ has a single tranny cooler AFAIK) and there are plenty of us that haul some VERY large toys to pull behind them. The 1FZE would pull some of said toys but it would definitely let you know it alot sooner and do it alot slower! Pretty much with the 2UZ what we're seeing so far is change the oil, t-belt, and starter contacts and keep on rollin'. Unfortuately it just doesn't have a list of selling points to talk about other than being reliable.
Hope this helps.