If you have an lx450 or system with auto A/C button. I have found some of those cruisers had a factory cell phone installed in them. There was a feature that when the phone was being used it would send a signal to the A/C amplifier to put the fan in low fan mode. Even if the fan button was showing in high. One of my customers had this issue for several years after he had the phone removed but the cradle was still in place. It's also possible that wire going to the A/C amplifier is grounding out or something in the amplifier is bad. I only found the wire on an lx450 diagram and ended up just cutting it at the harness and magically everything came back to life. I'll try and dig up the diagram.