Orange peel is as natural as it comes. Conditions have to be absolutely perfect for paint to go down everytime smooth as glass. I've been painting for over 20 years and only occasionally do I get perfect finish. Most painters will agree, the real quality comes from cutting and buffing AFTER the paint is dry. You can get all sorts of things in the paint, on the paint, or lumpy runs or orange peel, but how you treat it afterwords is what makes the final product.
Most finishes will say you can recoat within 24hrs without sanding (mechanical adhesion). It is important to atleast have two good coats of material in order to have enough to sand without going through.