Do you have any issues with the weight sensors with all this weight?
Do you mean the height sensors? The AHC simply measures the height of each front corner, and the rear axle, and pumps oil into the system, or releases some, until the correct height is achieved, with some exceptions.
If you mean the height sensors, no, I haven't had trouble with them.
If you mean pressure sensors within the system, the weight of the vehicle i still pretty close to the GVM, unless fully loaded, so I'm hoping that the pressure sensors, used for things like pump cut-off, oil return bypass and such, can cope with the extra pressure. That could be a misguided hope.
However, I did replace all four spheres because they had lost pressure and I had a bouncy plus hard ride. I used rechargable third party spheres with custom pressures in them, from Keith Bowers at
Active Suspension Systems. I also adjusted the torsion bars to carry more weight. The rear springs had already been upgraded to carry extra weight. Which ones I used are in posts around here somewhere . . . ah yes, Old Man Emu (OME) 862 springs from ARB.
Anyway, the fix using new spheres lasted a few months, then the problem gradually returned for the front axle. The rear still seems to be fine. I haven't fixed that problem yet, with other things like life getting in the way, so I have a bouncy and hard ride at the front again. The spheres could have lost pressure, or it could be a problem with air/gas in the lines, which are a pain to bleed properly, especially from the hydraulic rams.
It could be a problem with the front actuators, such as worn or stuck valving, stuck or blocked return line, or god knows what. All I know is that I don't want to pay Lexus to fix it, since they just replace something until it works again, at great cost to the customer. So I have to find/make time to investigate properly, and potentially find somone to recharge my spheres.
So, if your real question was, "Does it all work with all that weight on it?" The answer is yes, for a while. Can it be maintained? Maybe, but I don't know as I don't know why it isn't working properly now.
I suspect that to really make it work with lots of extra weight on the LX, you should both increase the spring rates and increase the dampening. Because I can't really redesign/rebuild the Actuators, which do the dampening, the only way to increase dampening is to increase the viscosity of the oil use. I haven't looked into that yet.
Not much help really, am I?

I guess if you do it, you take the risk that you will have the same problems as me in a few years.
Note that my suspension worked fine for over six years after I added all the weight, and I used the LX on some very serious 4WDing trips. So it isn't like the AHC fails under more weight immediately.