You have to drop the ds and get the transmission unbolted. There are some connectors on the trans that are a bit of a pain, but the big problem, at least for me, is the transmission bolts. There are several guys on here who said they were able to get them with 30'' worth of extensions. Others are unbolting the motor mounts and lowering the engine a bit to get the access. That should give you an idea of what your in for.
Also, are you sure its your rear main and not your oil pan seals leaking ? The oil pans on these trucks are a common leak area and can make you think its the rear main.