Make, model, year goes a LONG ways in determining a problem. Then little things like, I hear it in the front, rear, left or right, and it's more of a wobble, wobble, wobble or a SKREEEEE!, or wappity, wappity, wappity kind of noise. Does it happen when you apply the brakes, or shift it into neutral, or when it's hot or cold, or when it's over 100°F?
Some people even post a YouTube video to help with internet diagnosis from all the experts here.
I'm thinking you're low on blinker fluid and and when you reach the critical speed at 65 MPH, the centripetal force is causing the air to rush past the opening and causing a whistle, that , when muffled by the tire noise, ends up more like a screech.
Good Luck! I hope that you are able to isolate the problem and gather more assistance.