Personally believe that it can’t happen. Prove me wrong! 

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The factory switch only has two wires coming out of it (besides ground). One for the main on/off as you mentioned, and one that sends different resistances to ground (as I understand it) into the cruise control module for resume/accel, set/coast, and cancel. That won't work with the LS swap stuff...I don't know what the op is trying to do. Afaik from memory the dbw Cruise control is pretty simple wiring. I could be remembering wrong. The factory switch should work fine. The only issue is the on off for the cruise is momentary on the toyota switch which won't work. So you have to work around that of which their are several easy ways to do so