Definately check out the Rogue Valley area. The

and I just had a couple friend move away from here back to Arizona (to be closer to family). He was a grade school teacher, she was a nurse (surgery IIRC).
Rogue Valley Medical Center is one of the better hospitals on the west coast, and certainly the best one in the Southern Oregon/Nor Cali area.
Home - Asante
Teaching is a bit harder around here. There's been some major cut backs in the school district (like many other places), so I don't know how much hiring they are doing.
Medford School District 549C - HOME
There are also several private schools around here, if that's your thing:
GRACE CHRISTIAN SCHOOL
http://www.cascadechristianhigh.org/
St. Mary's School | Welcome!
That's just for the Medford area. There's also the Providence hospital in Medford, and a hospital in Grants Pass (also Asante) and Ashland (seperate from Asante or Providence). There are other school districts for Grants Pass, Ashland, and a bunch of little ones around the area.
Don't know what type of nurse she is, but there are a
ton of medical establishments around here. The Rogue Valley is a big retirement spot, and has been for years, so the medical industry has been growing like crazy for years (and still is, despite the recession).
As G said, Medford isn't super metro. We're a decent sized town, but relatively small. The nice thing about this area is you can live out in the woods, and still be only 30 mins away from town.
IMHO, the Rogue Valley has the best weather of all of Oregon. We have 4 distinct seasons, but nothing that is extreme. Couple weeks to a month of really hot (100* weather), couple months of really cold weather, nice weather the rest of the year.
On the eastern side of Oregon (Bend and east) you tend to get quite warm in the summer, and quite cold in the winter. (It is high desert, after all.)
On the western side of the mountains, the Eugene area gets the most rainfall of any city on the entire west coast (volume wise, not per day). It also has the highest pollen count, which is a bummer for anyone who has allergies.
The Portland area is very beautiful. They tend to be a bit cooler and rainier than Medford, though not as much rain as Eugene.
The coast is pretty mild year round, the locals break out shorts and bikini's as soon as the weather hits the low 70's, and start complaining about the heat if it breaks 80*. They don't tend to get as cold in the winter as the rest of the state, but they get some spectacular winter storms. Oregon beaches tend to be cold and rocky.
Maybe you could provide some more interests/etc? Is there anything that you are looking for activity/sports/etc wise?