Answer from Holley why they do not recommend the 470 Truck Avenger for V8 applications:
"A 350 may create too strong of a booster signal with the 470."
That means they've designed the booster venturis taking into account that most I-6 engines have such restrictive intakes and exhausts that they have difficulty in dropping vacuum to very low levels, while a V8 generally does not have this problem and can reach 0"hg or thereabouts easily. This means that not only more fuel may be pulled, but that the fuel (remember this is an emulsified air/fuel mix at that point) may be atomized into much finer droplets. This *may* allow the fuel droplets to actually vaporize, especially in a hot engine on a hot day. When fuel is turned to vapor, it takes up more volume. (Water is similar. When turned to steam it expands 180 times.) This means that the intake charge loses volumetric efficiency, effectively reducing the size of the engine. Not really a big deal for a stock V8, but a big issue for a racing V8.
One big reason for the using more efficient boosters is for better fuel metering at low RPMs, ideal for a lugging I6. But V8s can lug down too. I'm doing quite well with a stock 350 with a Quadrajet and small tube headers. It's almost as good as an I6. Huge difference between the Quadrajet and the 670 Truck Avenger, which would not lug down at all.
So the big question is... will the 470 TA work on a stock small block? Especially one that you want to lug with and isn't run to high RPMs. I'm still of the opinion that it will work. But given Holley's answer it is not ideal for a small block that's not stock, or is used at WOT often. Consider this... Holley does NOT say the 470 is not ideal for a modified I6 or V6. Those installing a 4-bbl intake on an I6 will likely be installing a bigger cam and better exhaust. There goes the arguments for reduced efficiency of the engine. There has to be some overlap with a V8 at that point. That's why I believe a 470 will work on a bone stock small block that's not treated like a hot rod engine. But this is just my opinion.