I don't know anyone with enough miles on one to say seeing as they are so new.
I'm guilty of grouping them in with the 4l60e/65e/70e as I see them as the factory offering all the same upgrades done when rebuilding an earlier transmission.
IMO, 4L80E first gear is not very great and 4L60E/70E/75E are hit and miss. Some guys can get 400K miles from one and others go through one every 30K miles. I don't know what makes the difference, but I am not one of the guys that has seen a long life from a GM automatic. I would lean towards...