Since you are new to towing with a 200 series, there is a good, rich (and admittedly sometimes overwhelming) thread on Towing with a Land Cruiser somewhere on this forum. That said, I think many of the critical points have been addressed already in this thread. I have towed 2 travel trailers, similar in size. Both approximately 6K# GVWR. First 3 years towing throughout Colorado. This past year here in Oregon. I choose to go “by the book” 90% of the time. S6 (2016 LC w/ 8-speed) and ECT to start. Downshift when appropriate in order to manage speed on descents, especially curvy descents. Sometimes I’ll downshift going uphill if it seems like the tranny is hunting. I like to see the RPM in the low 3,000’s but its not the end of the world if it is higher or even in the high 2Ks for a bit. I just prefer that it is not always switching or that it “lugs down”. As for Cruise I will occasionally use it on the flats to give my leg a break. But I tend to err on the side of caution. Where @linuxgod is carefully monitoring all of his systems and therefore will push LC much further than I care to. But he has to drive all the way from Chicago!
I just find that when I am towing I just slow everything down. I relax a bit more. But my trips tend to be up to 5 hours with a couple of breaks. Not the long hauls that some folks are doing.
Bottom line is that the 200 with its engine and sturdy suspension and weight seem to make it a very solid towing platform provided you stay safely within the tow weight and tongue weight ratings. (Also, since my trailers have been over 5,000# I use a weight distribution hitch.)

Bottom line is that the 200 with its engine and sturdy suspension and weight seem to make it a very solid towing platform provided you stay safely within the tow weight and tongue weight ratings. (Also, since my trailers have been over 5,000# I use a weight distribution hitch.)