Just to be clear - I didn't put anti-sieze on the face of the nut intentionally. I did it through ignorance (some could say stupidity...). I put it on the threads, prolly more than was necessary, and some got on the nut. Sloppy, perhaps. Didn't know it would be a problem. Some things you learn by fxxxing up.
But this is about the original poster, who's having multiple stud failures...based on my own experience, I would guess there is a scenario where (over the course of 280,000 miles) the nut/wheel interface had less friction than it should, and the studs got stretched.
Eventually they will fail. Replace them. Drive on.