If you like beer, you're in Beer Heaven East of the Rockies. So many fantastic breweries, as mentioned:
- Wicked Weed is an experience, food is ok, it's more about the overall experience.
- LAB has fantastic/creative food, decent beer.
- Sierra Nevada deserves a half-day excursion. The brewery and grounds are amazing; great food and beer, so much to do there.
- Highland Brewing is the grandpappy of the A'ville brew scene, it's a very cool place that hosts food trucks, live music, and has great beer.
Then just for pure hoppy pleasure, there are another dozen or more: Burial and Green Man are 2 of my favorites (very laid back), Wedge, One World, Hi-Wire, etc etc etc.
Tupelo Honey is an institution, likely worthwhile for breakfast or lunch if no line. Our last trip, Salsa really impressed us.
Whatever you do there, enjoy it. Asheville is a trip, never know what you'll see/find/experience. Taking a break from Biltmore, the downtown area has good shopping (according to my wife), arts, music, an amazing chocolate shop - just walk around and you'll find many things to do......