Well I think that combo is going to be great, as you can see in my posts. the modifying of the driveshafts and trans cross member depends on where you mount the motor. Since there are numerous ways to mount the motor everyone's answer will be different. Typically, there is a slight modification to trans cross member and driveshafts. There seems to be about 3 main ways to mount the motor, Selkirk motor mounts, cruisermatts from his shop, or FAB your own. Each will have its own set of peculiarities. Not sure where you are in vehicle prep, but you have time to plan that out by getting the truck ready first, a lot of degreasing, and front end work can be done!
Do not forget to tap and helicoil Marks Adapter, the aluminum threads suck.