My truck has a 4" lift and is on 35"s with stock gearing. I would love a set of 3.70s since I like to drive around 72 mph on the highway and even with my tires that spins my engine to around 2600-2700 rpm I believe.
3.70s would hurt your economy IMO. I had 35s on mine, and 4.11s, with 4.11 gears it was a little sluggish taking off on hills, and really too highly geared in steep off road conditions. These engines are happy at the RPM you are cruising at.
With taller gearing, you'll have to feed in more fuel to get it moving and for hills etc due to a reduction in torque at the wheels. Economy is not likely to improve