I made the female connectors to existing factory connectors. make it clean and easy. but you need some basic electronics capability including make wire harness, crimping tools, hunting for connectors.
for example, for 06 LX, the majority of speaker wires comes from these two connectors:
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two front door speakers, however are from mayday ecu connector and Nav computer connector:
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depending on your years/model/configuration, you may need to check all those connectors. the common speaker wire connectors (S18,S19 for example) are toyota standard ones and easy to find the female connector for them. the Mayday and Nav connectors are not easy to find if you have them. you can remove the whole mayday system and reuse one of the female connector. I can source most of the connector from Japan or China.
again, YMMV.