There are a couple of issues with making a quick connect tire carrier. One is the spindle cap. The spindle cap could be replaced with a machined cap that screws in. Catch is that it would take a $1 part to a $25 or more part. So the price increases.
Removing the cotter pin and nut etc is easy, but now you have have to deal with the spindle being exposed. So that means we have to make a sleave that screws on seals it from the environment. Another low volume high cost part to make, or you have a. dummy hub. Again cost.
In addition, you have to disconnect the lights for the license plate and any antenna's/ backup lights you have on it.
Granted one could put quick connects on all the electrical connections. but the catch is the license plate itself, unless you figure a way to mount it to the bumper instead of the carrier. I could not without it being prone to damage.
So, yes it could be done, but will add to the cost.