If you have an external pump and it's at least lower than the surface level of the fuel in the cell, it's going to be getting positive fluid pressure in the feed line as long as the flow rate in the input hose doesn't exceed the flow capacity. It shouldn't, especially if you're plumbing half inch hose into the pump and 3/8" out. The siphon effect just helps me know that whatever sub-atmospheric pressure the hose run is experiencing at the top, it's re-pressurized by the time it gets back down to the pump. It's better with the pump below the tank than if it were sitting right on top.
There's a lot to be said for having all the fittings come out of the top of the tank. Gasoline has a way of wetting it's way around seals and threaded fittings. It's not "leaking" per se, but when you see the dust collect on the surface, it'll be matted into a slightly greasy mud around the fittings and you can tell that the only reason for that is tiny amounts of gasoline on the surface. I've seen that a lot, and not just on my own rig. I'm pretty certain it's not my imagination.
The key thing in my fuel system is the Walbro fuel pickup array. If you've seen these, then I apologize for posting uselessly, but they were new to me when I learned about them and I was pretty impressed by the concept. They're apparently designed for snowmobiles:
The idea is that while the thing is below fluid level, fuel flows through the mesh. Once the fuel cell is tilted so that the pickup goes into the air, the wetted mesh acts like an air-proof diaphragm. Behind the mesh there's a spring loaded valve. If the fuel system starts to draw suction, atmospheric pressure closes the valve.
I've got 4 of these plumbed in an H pattern so that one's in each corner. In theory, even at low fuel levels and weird angles, one of these should be below fluid level at all times. If the others are in the air and start to "suck", they'll shut and the fuel will continue to be drawn from the submerged one(s) without bubbles. Thanks to this, I didn't feel it necessary to consider a sump or fuel catching baffle system... but then again, I'm seldom down to a quarter tank.
Also... the mesh on those pickups is 70 micron. It's a bit of a pre-prefilter.