I suspect most of our problems will come from irritating humans in RVs.
Critter jams of one sort or another will be a constant annoyance. Expect at least one any time you go anywhere, and be thankful you don't have to deal with one when that happens. After a few critter jams it will become, Oh, they stopped for bison, groan... At least they won't be as bad as they get in the summer.
Due to the distances in the park, seriously consider doing lunch, and maybe dinner out of the back of your vehicle. You will have to either store your food in a bear vault at the campgrounds, or take it with you during the day and keep it in your "trunk". In fact all food, toiletries, etc. must be stored in a bear proof manner when not in use. In campgrounds they recommend storing it in your locked trunk or in a bear vault. YNP and GTNP don't have canopener bears yet, and they want to keep it that way. Problem bears are dealt with quickly, and the way to keep them from becoming problem bears is to never let them get human food. That way the bears don't associate humans with food. YNP recently had to put down a bear that got human foods and became aggressive.
I do all my eating out of the back of my truck. I just love the looks on people's faces when I grill a steak, do stir-fry, make omelets, or waffles at a pullout.

Yeah, you don't have to eat at a picnic area. Just don't leave crumbs or other food bits behind. Also all waste water, like from washing dishes, must be collected up and disposed of down a drain. Drains for that purpose are at most campgrounds. People also dump it down the pit toilets. Wherever I cook a meal I check around for bears and bear activity. I also stay alert for them showing up mid meal. Also be mindfull of the wily coyotes and ravens. I've seen them snatch food out of people's hands.