I assume you have a 2008-2015 6-speed cruiser?
You'll be 10% over-geared with 35s, with some requisite efficiency loss, but generally is fine. 4.3s are more ideal and too many subscribe to the more is better. There's a balance.
33s will only make is worse with higher RPM and windage losses. Though aero and tire rolling resistance is a factor too, perhaps more significant to MPG
Here's a reference and tables
EDIT: Expanding tables for 8-speed and 40s
So I had a little time this morning to put together a chart combining transmission gearing of 6-speed vs 8-speed, diff ratios, and tire sizing into an overall gearing reference. Hoping this will be useful for those trying to understand how their changes are going to effect overall gearing of the setup.
EDIT: Adding additional reference info
Few notes:
1) Yellow and Red denote marginal to poor ratios for the setup
2) Even with 37s, the 8-speed first gear gearing is better than the stock 6-speed gearing with 31s!
3) The 8-speed has...