Just so we are all clear, the 2uz-fe does not have hydraulic lifters and therefore their is no reason for them to fail. The clearance between the camshaft and the lifter bucket can change (although it rarely does) but the lifter cannot fail. The lifter in a 2uz-fe is solid chunk of steel, there are no moving parts. The clearance is adjusted with shims. It does not have a hydraulic lifter which uses oil pressure to maintain a proper clearance. Hydraulic lifters fail.