Basic physics of welds makes the "weaken/crack the actual pipe" pretty unlikely. Enough so that I wouldn't worry about it. The break should follow the weld hardened zone and stress riser of the tab long before it affects the relatively stress riser free pipe.
Could be ... and I will ask my son (who managed to teach himself some mandarin) in EnSci at UofT to gather up his brilliant Chinese buddies to write a paper on this (which I wont understand!) in the interim I am betting on two things I DO KNOW:
1) if the metal used to form the tab is stronger/thicker etc than the tube wall - the tube wall will fail where the heat of the weld has annealed (softened) the tube wall -- ie the tube wall will fail before the tab, and 2) Murphy's law -- a well accepted principle of physics will prevail.
Now I understand that this would not be catastrophic as you can always bypass the tube with a length of hose -- not as elegant but just as functional. And if Pinhead is correct you can always purchase a new tube cheaply (?) and reinstall it without the lower bolt. But as I live in Canada and US dealers are not supposed to ship parts to me in Canada and Lexus Canada have decided to place a usurious profit margin on every part I purchase from them ... I would not go that direction if I can avoid it.