I found 285/65/18 KO2s overwhelmed the stock suspension based on the significant weight increase and IMO a bigger factor here, the higher required pressure. Sharp bumps in particular sent reverberations through the chassis, and this wasn’t a thing at all with the stock p285/60r18s. That said many people like this setup, maybe I’m just too picky about how suspension and tires work together.
Mine is a 2013 but had new factory toyota dampers on it at the time, so should be a lot like a new 21.
Also not sure whether this is a factor for you but your mileage will drop when switching from P-metric to LT-metric.