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No, I don't think so. I run synthetic in one of my cars (supercharged pontiac with 22,000 miles), 5000 mile change interval. I run Rotella in the other cars. 10W 40 in the Cruiser, 15W-40 in the oil burning town only driving car.
I will say that with the Rotella, I saw no wear after 8000 miles on the camshaft and lifters. The surfacing grind marks were still there.
I would run synthetic if:
It was a high performance engine
it was a high revving engine
it sits not running for more than 9 months at a time
I wanted extended change intervals
That is my $1.50
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